Phentermine HCL and Phentramin-D are two different types of diet pills primarily used to suppress appetite, increase energy, and improve one’s metabolic rate. Below is a detailed explanation of the primary differences between the two.

Phentermine diet pills are an FDA approved appetite suppressant that requires a doctor’s prescription. They first approved by the FDA in 1959, and then made available as Phentermine Hydrochloride in the 1970s. Most common side affects of Phentramine are insomnia, irritability, increased blood pressure, and nervousness. Like many prescription drugs, Phentermine affects neurotransmitters in the brain by stimulating neuron bundles and thereby releasing catecholamines such as dopamine, epinephrine, and norepinephrine. This effect on the central nervous system is what is believed to alter eating habits. Some critics of Phentermine compare its affects to those of amphetamines. However, when the popular diet drug Fen-Phen was removed from the market in 1997 due to numerous health concerns, the FDA took no action against Phentermine. It is generally recommended to be taken as a short-term drug, with a usage limit of 12 weeks.

Phentramin-D, on the other hand, is a chemical compound consisting of dimethyl-pentylamine-hydrochloride and trimethylxanthine, and it has not been approved by the FDA, nor does it require a prescription to purchase. The result of the chemical compound is a sympathomimetic amine similar to Phentermine, which mimics the effects of norepinephrine, causing increased energy and elevated metabolic rate, without affecting the central nervous system like Phentermine. Because the name is similar to Phentramine, some people mistaken it for an herbal product, but this is not the case. Side affects of Phentramin D include dry mouth, sleeplessness and irritability.

While the effects of both Phentermine and Phentramin-D are similar, results vary from person to person. The most significant difference between the two is that Phentermine behaves similar to amphetamines, and of course the use of amphetamines has become widely unpopular in recent years due to new information about their negative impact on health. At the same time, even though Phentramin-D is comprised of a chemical compound, it has yet to be approved by the FDA, and is a relatively new product.